Actoplus Met (Pioglitazone HCl-metFORMIN HCl)

Alternate Name: Pioglitazone HCl-metFORMIN HCl

Dosage Form: Tablet

Administration Route: By mouth

Drug Class: Hypoglycemic

Generic Available: Yes

Strength: 15-500 MG

Warnings: Keep all medicine out of the reach of children. Never share your medicine with anyone. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. It is important to tell your doctor or dentist that you are using this medicine. You may need to stop using this medicine several days before having surgery or other procedures. Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may interact with the dye used for an x-ray or a CT scan. This medicine may cause the following problems:Congestive heart failureLactic acidosis (too much acid in the blood)Low blood sugarLiver problemsIncreased risk for bladder cancer if you use this medicine for a long timeIncreased risk for broken bones Tell your doctor if you have kidney disease, liver disease, heart failure, edema (fluid retention or swelling), macular edema (swelling of the back of the eye), adrenal or pituitary gland disease, vitamin B12 deficiency, or a history of alcohol abuse or bladder cancer. Tell your doctor if you are pregnant or breastfeeding. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine. Some things that can lead to low blood sugar are exercising more than normal or waiting too long to eat. Tell your doctor about any sudden change in your medical condition. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You will also need to check your blood sugar on a regular basis at home. This medicine may increase the risk for bone fractures in women. Ask your doctor about ways to keep your bones strong to help prevent fractures. Check with your doctor if blurred vision, decreased vision, or any other change in vision occurs during your treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). Shortness of breath with cold sweat and bluish-colored skin. Severe vomiting with fever or diarrhea. Unusual weakness, bruising, or pale skin. Swelling in your hands, ankles, or feet. Yellowing of your skin or the whites of your eyes.

Food Warnings: Check with your doctor if blurred vision, decreased vision, or any other change in vision occurs during your treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor)., Do not drink alcohol while you are using this medicine., Limit how much alcohol you drink., Some things that can lead to low blood sugar are exercising more than normal or waiting too long to eat. Tell your doctor about any sudden change in your medical condition., This medicine may increase the risk for bone fractures in women. Ask your doctor about ways to keep your bones strong to help prevent fractures., Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You will also need to check your blood sugar on a regular basis at home., Some medicines can affect how this medicine works. Tell your doctor about all other medicines that you are using, including the following:Acetazolamide, cimetidine, dichlorphenamide, dolutegravir, gemfibrozil, isoniazid, nicotinic acid, phenytoin, ranolazine, rifampin, topiramate, vandetanib, zonisamideBirth control pills (including estrogen)Blood pressure medicineDiuretic (water pill)Insulin or other oral diabetes medicineMedicine to treat mental illnessSteroid medicineThyroid medicine, Check with your doctor right away if you start having chest pain; shortness of breath; excessive swelling of the hands, wrist, ankles, or feet; or if you are rapidly gaining weight. These may be symptoms of a serious heart problem., This medicine may cause a rare, but serious condition called lactic acidosis in some people. Call your doctor right away if you get sick, or if you have unusual tiredness, weakness, muscle pain, stomach pain, trouble breathing, fever, or nausea., Tell your doctor right away if you have any of these symptoms: loss of appetite, nausea, vomiting, stomach pain, unusual tiredness or weakness, weight loss, or yellow eyes or skin. These may be symptoms of a serious liver problem., This medicine may increase your risk for bladder cancer if you take it for more than 12 months. Tell your doctor right away if you have blood in the urine; a frequent, strong, or increased urge to urinate; painful urination; or pain in the back, lower abdomen, or stomach.