Methotrexate Sodium (Pf)

Alternate Name: Methotrexate Novaplus

Dosage Form: Vial

Administration Route: By injection

Drug Class: Antineoplastic Agent, Antirheumatic, Antirheumatic, Cytotoxic, Antipsoriatic

Generic Available: Yes

Strength: 50 MG/2ML

Warnings: This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children. This medicine may cause the following problems:Stomach or bowel problems, including ulcer or perforationLiver problemsBrain or nerve problemsLung or breathing problems, including interstitial pneumonitisKidney problemsSerious skin reactions, including toxic epidermal necrolysis, Stevens-Johnson syndrome, exfoliative dermatitis, skin necrosis, or erythema multiformeIncreased risk of cancer (including lymphoma)Nerve problemsTumor lysis syndrome (electrolyte and metabolic problems that can be life-threatening) This medicine may make you dizzy or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds. This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Female patients should use an effective form of birth control during treatment and for at least 6 months after the last dose. Male patients who have female partners should use an effective form of birth control during treatment and for at least 3 months after the last dose. Do not breastfeed during treatment and for at least 1 week after the last dose. Tell your doctor if you have kidney disease, liver disease, blood or bone marrow problems (including anemia), lung or breathing problems, diabetes, a weak immune system, any type of infection, stomach ulcers, or a history of alcohol abuse. Tell your doctor if you are also receiving radiation treatment. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need chest x-rays. Keep all medicine out of the reach of children. Never share your medicine with anyone.

Food Warnings: Some medicines can affect how methotrexate works. Tell your doctor if you are using any of the following: Azathioprine, hydroxychloroquine, mercaptopurine, nitrous oxide, phenylbutazone, phenytoin, probenecid, sulfasalazine, theophyllineMedicine to treat an infection (including chloramphenicol, penicillin, tetracycline, trimethoprim/sulfamethoxazole)NSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen)Retinoid medicineSteroid medicineStomach medicine (including esomeprazole, lansoprazole, omeprazole, pantoprazole)Vitamin supplements containing folic acid, Do not drink alcohol while you are using this medicine., This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines., This medicine may cause the following problems:Stomach ulcer or perforationLiver or lung damageSerious skin reactionsHigher risk of lymphoma (cancer of the lymph system)Tumor lysis syndrome (high levels of electrolytes or minerals in your blood), This medicine may make you dizzy or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you., This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often., This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds., Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need chest x-rays., Keep all medicine out of the reach of children. Never share your medicine with anyone.